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Diagnosing and Treating Depression in the Primary Care Setting: It Can Be a Depressing Experience for the Primary Care Physician


Epidemiological and clinical research over the past two decades has shown depression to be a common and highly debilitating condition. Depression can exact high costs in terms of work productivity, the success of personal relationships and general satisfaction with life.

For the family physician in a primary care setting, however, the depressed patient poses enormous challenges of diagnosis and treatment. A growing body of research, to which Michael Klinkman, associate professor of family medicine, Thomas Schwenk, professor of family medicine and chair of the Department of Family Medicine, and James Coyne, formerly a member of the family medicine faculty at Michigan and now at the University of Pennsylvania, have contributed significantly, suggests a developing awareness of the shortcomings of the “top-down,” diagnosisdriven approach to mental health care in the complex world of primary care, but the absence, as yet, of a clearly articulated “bottom-up” approach that will provide a more accurate view of mental health problems as they exist in primary care. Classic psychiatric instruments for screening depressed patients don’t seem to work very well in the primary care setting, but the question of what will work is still unanswered.

In several recent articles, Schwenk, Klinkman and Coyne discuss the results of a study they undertook involving 425 adult patients in the family practice setting. The study suggests that there are significant differences in the past history, severity and impairment of depressed patients in the primary care setting and those in a psychiatric setting, that primary care physicians are nevertheless pretty good at identifying patients who are overtly psychologically distressed, but that they miss significant numbers of depressed patients who are different from the overtly depressed patients in psychiatric settings who provided the basis of their medical training.

Depression, they say, is an important diagnosis but often an elusive one, and for the primary care physician, diagnosis and treatment of the depressed patient can be downright daunting. Depression in different patients doesn’t always look the same or act the same: some patients get depressed only when they’re under stress, others are depressed much of the time. In some ways, Klinkman and his colleagues have found, depression in the primary care setting can look and feel a lot like asthma and diabetes in the sense that they are all chronic conditions requiring not only good diagnosis and treatment, but patient energy and attention as well. “You can tell asthma patients, ‘You’re breathing at only half your capacity,’ and suggest they use their inhalers, but some of them will elect not to use the inhalers even if their breathing is greatly reduced. It just isn’t their highest priority,” Klinkman says.

And there are other reasons depressed patients may not respond. Not all patients view depression as a legitimate medical problem; they may think mood disorders are inappropriate for a doctor’s attention. Some physicians may be less or more likely to identify depression in a patient depending on the patient’s gender, age and ethnic derivation. Many physicians feel they just don’t have time to explore psychosocial issues, no matter what the patient’s level of depression or gender, age or ethnic background. Even when the primary care physician does correctly identify the depressed patient, the diagnosis may not necessarily lead to an improved outcome for the patient, since depression is not easily treated.

The complexity of their findings has led Klinkman and his colleagues to come to at least three major conclusions:

  • A “snapshot” diagnosis doesn’t work with the depressed patient in the primary care setting; one has to take into account the passage of time, how the patient performs over weeks and months and years, not for a few minutes in a clinical setting.
  • Blaming the physician because the depressed patient doesn’t improve is missing the big picture; much is still not known about how best to approach depression in the primary care setting and the attitudes and value systems of patients must also be taken into account.
  • How and when the primary care physician should intervene is a matter of priorities, of communication and decision-making. Having the physician engage in a onetime, stand-alone consultation with a psychiatrist as well as having the patient engage in brief, diagnostic consultations with a psychiatrist may be beneficial. (Such consultations, Klinkman suggests, can be as important for the relief they provide the physician in sharing the caregiving burden as for the information they provide.)


“We think we know what doesn’t work very well,” Klinkman says. “Our next challenge is to find out what does work.”


For more information, see the following articles:

  • “Depression in Primary Care...More Like Asthma than Appendicitis: The Michigan Depression Project, Canadian Journal of Psychiatry, November, 1997
  • “Depression in the Family Physician’s Office: What the Psychiatrist Needs to Know,” Journal of Clinical Psychiatry supplement, September, 1998
  • “False Positives, False Negatives, and the Validity of the Diagnosis of Major Depression in Primary Care,” Archives of Family Medicine, September/October 1998


You may reach Michael Klinkman at mklinkma@umich.edu


You may reach Thomas Schwenk at tschwenk@umich.edu

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