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THE STEPS TO AGILITY IN OLD AGE: “GAIT GUY” NEIL ALEXANDER IS WORKING TO FIND THEM

By Jane Myers


Neil Alexander
Neil Alexander

Living forever (or even just into your 120s or 130s) is one thing. Being able to walk and run and sit and stand and climb stairs in your 60s, 70s, 80s and 90s, is another.

For Neil Alexander, M.D., associate professor of internal medicine and a senior associate research scientist in the Institute of Gerontology, the fountain of youth once associated with dreamy explorers of the past like Ponce De Leon and now associated with dreamy explorers of the future, is still just that—dreamy. Perhaps it’s the giddiness of millennium fever, but when “The Exploding Science of Superlongevity—Our Life Span Revealed” is part of the fluorescent orange cover of the January, 2000, issue of Wired magazine, it’s clear that living forever is “in.” Never mind forever. Neil Alexander has more modest hopes. “We’re just trying to slow the decline in functional ability,” he says of his research on mobility in older adults. In other words, making it possible for people to keep moving, to perhaps lift themselves off their chairs and stand up to blow out those 78 or 84 or 96 candles on the cake, maybe even do a little dance around the table.

Neil Alexander began his academic career at the University of Minnesota thinking he’d study child psychology. But when, for his senior honor’s thesis, he tried to train a group of junior high school students to do volunteer work in a nursing home, a whole new field of inquiry, one involving subjects at least a half-century older than his teen-aged volunteers, opened up before him. “I didn’t know what to tell the kids,” he recalls. “There wasn’t a lot of good information out there that was scientifically-based about working with older people.”

At first he was simply interested in the whole subject of geriatric rehabilitation, but when he looked closer and realized how little true science had been applied to the subject, he headed for the lab.

Ten years later, he’s pleased that he’s established a national reputation as a “gait guy” (also a “fall guy”) and that he and his biomechanician collaborators, as he calls them, were able to contribute a chapter to a major geriatrics textbook, Principles of Geriatric Medicine and Gerontology (McGraw Hill, 1994), establishing themselves as major movers in the area of geriatric mobility.

The subject of mobility and aging, and the consequences of time, life habits and disease, is not as simple as it might at first seem. “There is an accumulation of things over which you may or may not have control,” Alexander says. And then there’s the whole psychological component of aging, one not to be taken lightly in a youth-obsessed culture. “We want to start looking at people in their peri-menopausal years—their 40s, 50s, 60s,” he says. “Our theory, based on some anecdotal observations, is that they start giving up stuff. They express expectations of frailty and decline.” And, of course, there are the catastrophic events that people fear as they grow older, the strokes and hip fractures that cause, at least temporarily, sharp declines in mobility, that, at best, level out to the earlier rates of slower decline.

The focus of Alexander’s research, really, is to understand the mechanisms that determine whether or not a person can maintain good mobility as they age, and, at least, as he puts it, help to “make a dent in the slow slide.” When he looks at an act as clear-cut as getting in and out of a chair, Alexander now sees a sea of complexity involving not only the biomechanics of such an act, but the cognitive piece as well, which speaks to such factors as memory, affect, mental flexibility and visual/spatial acuity. And then there’s the chair itself, which falls into the large category of “environment.”

His work, and the work of his team in the Mobility Research Laboratory on the second floor of the Geriatrics Center, focuses on the key components of such a task, and the interventions that might help a person more easily get into and out of the chair. Understanding the mechanisms that underlie common motions should make it possible, eventually, to give people strategies that will, for instance, help reduce the number of falls in older people.

Alexander is keeping an open mind about what might work. He and his team are now proposing to add to their catalogue of potential “saves” such regimens as aerobic training, balance training and tai chi to see if they might help. Tap dancing perhaps? He doesn’t have that on the list, but he is presently developing ways to assess and train rapid foot movement to determine whether rapid stepping is important in maintaining mobility.

At the moment he and his team have plenty of analysis ahead of them. “We’re drowning in data right now,” he says. “But we hope before long we’ll have some good solid answers that will make a difference in the way people move and keep moving as they age.” If Alexander succeeds in his work, those 120-year-olds of the future may not be playing tennis — but they won’t be falling down either.

Also:

Will You Still Need Me, Will You Still Feed Me, When I’m a Hundred and Twenty-Four?

FUNDING FOR AGING RESEARCH AT THE UNIVERSITY OF MICHIGAN

VETERAN JOURNALIST DANIEL SCHORR HONORED AT U-M GERIATRICS CENTER CELEBRATION

 

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