What happens to Baby when Mom is depressed?
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Delia M. Vazquez
and Mark Isaacs, one of the children participating in
her study of cortisol levels in infants and mothers. Photo:
Martin Vloet
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Growing up with stress is not healthy for infants and young
children, says Delia M. Vazquez, M.D., an associate professor
of pediatrics and psychiatry in the U-M Medical School. Children
who live with chronic stress are more likely to develop depression
early in life. In extreme cases, children even stop growing
until their high-stress environment is changed.
To learn more about the relationship between a mother’s
depression and development of the stress hormone system in her
infant, Vazquez is involved in a long term study of new mothers
at U-M Women’s Hospital who have a high risk of developing
depression. By measuring a stress hormone called cortisol in
saliva, researchers can track the relationship between a mother’s
mood, the personal interaction with her infant and the normal
development of cortisol levels in her child.
“Cortisol follows a day-and-night cycle; it is high in
the morning and low at night,” Vazquez explains. “Cortisol
production in depressed patients is high when it should be low.
In contrast, children living in adverse environments, such as
third world orphanages, have low cortisol levels when these
should be high. We wonder if a child’s cortisol levels
would be a mirror image of their caretaker. Is there a set point
that is in part genetic and in part from their early life experience,
beginning during the first year of life? Can we intervene early
to stop a negative outcome, such as depression? How early? These
are the types of questions we hope to answer.”
Also:
Conquering
Depression
What’s
the best way to help depressed teens?
What
does stress do to your brain?
Can
primary care docs treat depression?
How
do antidepressants work?
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