Castle Elected as Fellow of AAAS

Valerie Castle, M.D. (Residency 1990), Ravitz Foundation Professor of Pediatrics and Communicable Diseases and chair, Department of Pediatrics and Communicable Diseases, is among five University of Michigan faculty members newly elected as Fellows of the American Association for the Advancement of Science (AAAS).

Castle’s many accomplishments include documenting the role of NF-kappaB activation in chemotherapy and radiation resistance that occurs in patients with neuroblastoma, a type of cancer that arises in nerve cells and affects mostly infants and children. NF-kappaB is a protein that turns on and off many genes involved in growth and development and plays a role in a number of diseases. Castle also is investigating pharmacological approaches to treating neuroblastoma.

Founded in 1848, AAAS is the world’s largest general scientific society and publisher of the journal Science.

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